Poisons – Getting Your Hands Dirty


Poison crafting is a great complement to the assassin playstyle as a member of the Dark Brotherhood in ESO’s new DLC

Hello all, Calia here; wearer of many hats. I play on PC, North America server. I’m guild master for the trade guild Iron Bank of Bravos,  PVP raid leader for Dominion Imperial Guard, and a member of Council of Nirn, a group that meets with Zenimax to provide feedback on ESO. I also have a hand in addons such as GodSend Guild Mail Tool and Thurisaz Guild Info. I’m here today to get down and dirty with some poisons.

With the introduction of the Dark Brotherhood DLC, Elder Scrolls Online: Tamriel Unlimited has brought about some long awaited gameplay changes and is letting players join the elusive Dark Brotherhood. This fabled group of assassins has a rich history throughout Tamriel and the Elder Scrolls series. Now what type of assassins would we be if we didn’t have poisons at our disposal? I’ve always been a fan of stealthy characters and rogue type classes, so I’m loving these changes. My main character is a Bosmer Nightblade, so I have loads of fun stealthing around and killing things.

This article outlines the major changes to Alchemy added with the new poison-crafting system. We have also made a number of big updates to the main Tamriel Foundry Alchemy Guide which includes a complete list of reagents and their properties, skill suggestions, leveling tips, recommended recipes, and more!


Basics – Making Poisons

There have been some changes to the Alchemy crafting line with the addition of poison crafting. What I’ve got in store for you is a handy reference guide that will help all you shifty individuals who are looking to dip your toes into toxic waters.

This DLC introduced 8 new Alchemy reagents, shown below. This now gives us a total of 26 reagents to work with. Each reagent has 4 properties (there are 30 possibilities), and it’s the particular combination of properties of your concoction that gives a desired effect.

New Reagents

Beetle Scuttle

Found killing insectoids like Thunderbugs, Shalk, or beetles

  • Decrease Spell Resist
  • Increase Armor
  • Protection
  • Vitality
Butterfly Wing

Harvested by collecting butterflies

  • Restore Health
  • Lower Spell Critical
  • Sustained Restore Health
  • Vitality
Fleshfly Larva

Found on corpses and from swarms of fleshflies near standing water

  • Ravage Stamina
  • Vulnerability
  • Creeping Ravage Health
  • Vitality
Mudcrab Chitin

Harvested from mudcrabs found throughout Tamriel

  • Increase Spell Resist
  • Increase Armor
  • Protection
  • Defile

A plant with bright purple blossoms growing in open areas

  • Ravage Health
  • Protection
  • Creeping Ravage Health
  • Defile
Scrib Jelly

Harvested from Kwama larvae called Scribs

  • Ravage Magicka
  • Increase Speed
  • Vulnerability
  • Sustained Restore Health
Spider Egg

Found on all varieties of spiders in Tamriel

  • Reduce Speed
  • Invisibility
  • Sustained Restore Health
  • Defile
Torchbug Thorax

The phosphorescent bulb of a common torchbug

  • Lower Armor
  • Lower Weapon Crit
  • Detection
  • Vitality

This is nearly identical to potion crafting; potions use waters, whereas poisons use oils. One slight difference you will notice is that with potions, you craft single units at a time; with poisons you create four at a time; this increases as you put points into the Chemistry passive. When fully invested with 3 skill points, you’ll be making 16 poisons with each crafting attempt.


Oils dropped in some zones may vary slightly depending on your character’s crafting level. Dungeons, along with undead, daedra and trolls are guaranteed to give you oils; just go to your zone level of choice to collect the ones you need.

Oil Level Rank Suffix Zones
Grease 3 1 I Khenarthi’s Roost
Stros M’Kai, Betnikh
Bleakrock Isle, Bal Foyen
Ichor 10 1 II Auridon
Slime 20 2 III Grahtwood
Gall 30 3 IV Greenshade, Malabal Tor
Rivenspire, Alik’r Desert
Shadowfen, Eastmarch
Terebinthine 40 4 V Reapers March
The Rift
Coldharbour, Cyrodiil
Pitch-Bile CP10 5 VI Cadwell’s Silver Zones
Tarblack CP50 6 VII Cadwell’s Gold Zones
Night-Oil CP100 7 VIII Craglorn
Alkahest CP150 8 IX Imperial City, Wrothgar, Hew’s Bane, Gold Coast

DBPoisonMakingAt this point, you may be thinking – how can I possibly know what to mix together? I’ve got you covered: here’s a helpful list I’ve been working on with a host of information. Check out the Trait Discovery tab to help you to discover the 4 traits for each and every reagent with the least possible combinations. Along the way you’ll gain not only an achievement for each reagent (who doesn’t love those!) but once you’ve discovered the traits for all reagents you will earn both the Toxicologist and Botanist Achievements, unlocking some new armor dyes.

Some items of note: At the time of writing this article, there are upwards of 2000 potential poisons, so myself and others are working to document them all on that link location, and it is updated frequently, so check back often!

There is a variety of information, including a Viable Reagent Combination Table, which you may find useful when trying to make new things.

The poison values noted there are based on using a Solvent Level 8 oil (Alkahest) so the poison values you get may not be the same.


I made some poisons, now what?

DBPoisonBladeWhile using poisons does provide some very distinct advantages, it is not without some costs, so there’s some things you may want to keep in mind. Poisons only apply about 20% of the time on light or heavy attacks as well as weapon abilities, and while they are slotted they will suppress your weapon enchantments.

It’s not recommended to keep them slotted routinely if you’re relying on weapon enchantments for other functions. Some people do keep them slotted, and if that’s your preference you should take your weapon’s trait and enchantment into account when factoring in what poisons you’d like to use.

To use the poisons, open your Inventory interface and you’ll see a space next to your weapons – that’s your poison slot. From here you can equip or remove poisons as you need to.


How do I know when the poison works?

Remember that whole 20% thing? Well, you’ll know when it happens – you’ll get a sound notification, and your weapon will get a glow around it, at which point one unit of the poison that you have slotted will be consumed.

Stay tuned for an updated Alchemy and Poison guide on Tamriel Foundry, and happy hunting my fellow assassins!

6 responses to “Poisons – Getting Your Hands Dirty”

  1. Profile Photo


    Total Posts: 3442

    Imperial Sorcerer

    Entropy Rising

    Awesome work @calia1120, this article is great overview, and the Google doc you put together is incredibly helpful. Thanks for all your help getting the main alchemy guide updated as well!

    Founder, creator, and developer of Tamriel Foundry.


  2. Profile Photo


    Total Posts: 1

    Altmer Sorcerer

    Awesome work there Calia! Thank you for this article. It’s going to help a LOT.

    Aleawyn – AD – CP 160 Sorcerer

    Nevariah – AD – CP 160 DragonKnight

    Azrael Loreli – AD – CP 160 Nightblade

    Azrael Sunchaser AD CP 160 – Templar

  3. Member Avatar


    Total Posts: 11

    Bosmer Nightblade

    Super helpful thanks!


  4. Profile Photo


    Total Posts: 58

    Bosmer Nightblade

    Tamriel’s Sentinels

    that was a great read, good job

    Shadow-Blood mage

  5. Profile Photo


    Total Posts: 12

    Breton Sorcerer

    Alchemy as it should have been at launch ;-)

    RPer for 30+ years.  Looking for other RPers to join the Dragon Tears in the Daggerfall Covenant!  PM me on the Bethesda Forums for info!

  6. Member Avatar


    Total Posts: 10

    Imperial Dragonknight

    I’m glad they added poisons the game just didn’t feel right without them.

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